Advertisement

Sanofi tests three-in-one antibody to treat or prevent HIV

Sanofi tests three-in-one antibody to treat or prevent HIV
From Reuters - September 20, 2017

LONDON (Reuters) - A three-pronged man-made antibody, created by French drugmaker Sanofi and U.S. scientists, could offer a new way to treat or prevent HIV, following successful tests in monkeys.

Plans are under way to try the so-called trispecific antibody in initial human trials before the end of 2018, potentially adding a new weapon in the fight against AIDS, assuming the product proves safe and effective.

If all goes well, the three-in-one antibody could be used either as a long-acting treatment or a vaccine, according to Sanofi Chief Scientific Officer Gary Nabel.

There is certainly urgency for a vaccine and this could help fill that void, he said in an interview. But we need to do the clinical studies and let nature tell us what works.

Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases, whose experts collaborated on the project, described the new approach as intriguing.

Unlike naturally occurring antibodies, the laboratory-made ones hit multiple biological targets in a single product - a feature that is particularly valuable in fighting HIV, given the huge genetic diversity of viruses around the world.

Advertisement

Continue reading at Reuters »