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Just one e-cigarette might raise adrenaline in the heart

Just one e-cigarette might raise adrenaline in the heart
From Reuters - September 20, 2017

(Reuters Health) - Smoking just one e-cigarette might expose users to enough nicotine to trigger an adrenaline surge in the heart that can contribute to high blood pressure and other health problems, a small experiment suggests.

For the experiment, researchers asked 33 healthy nonsmokers to come to a lab on different days to try an e-cigarette with nicotine, a nicotine-free alternative, and a sham device that wasnt a real e-cigarette. Each time, participants wore a heart rhythm monitor to assess variability in the time between heartbeats, an indicator of increased adrenaline.

People experienced increased adrenaline only when they smoked e-cigarettes with nicotine, and not with the nicotine-free alternatives or sham devices.

Smoking traditional cigarettes has long been known to increase adrenaline levels in the heart, and the current findings suggest that nicotine in e-cigarette emissions does this too, said senior study author Dr. Holly Middlekauff, of the David Geffen School of Medicine at the University of California, Los Angeles.

Inhaled nicotine delivered by e-cigarettes, traditional cigarettes and other tobacco products (e.g. hookah) rapidly enters the bloodstream and the brain and stimulates nerves that carry adrenaline and the adrenal gland to release adrenaline, Middlekauff said by email.

Perpetually increased cardiac adrenaline levels detected by abnormal heart rate variability are associated with increased risk for heart attack and sudden death, Middlekauff added.

Big U.S. tobacco companies are all developing e-cigarettes. The battery-powered gadgets feature a glowing tip and a heating element that turns liquid nicotine and flavorings into a cloud of vapor that users inhale.

Some previous research suggests vapor from e-cigarettes may be less toxic than traditional cigarette smoke, but the electronic alternatives still release chemicals that arent normally in the air and the long-term health effects of the ingredients and flavorings in e-cigarettes are unclear.

The current study doesnt offer a complete picture of e-cigarette safety or address the potential for health problems to emerge after long-term use.

But it does reinforce concerns about the heart risks of nicotine, the researchers note in the Journal of the American Heart Association.

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