BRCA gene mutation 'doesn't affect breast cancer survival'

From BBC - January 11, 2018

Young women treated for breast cancer have the same survival rates regardless of whether they have the BRCA gene mutation, a study suggests.

The BRCA1 and BRCA2 gene mutations increase a woman's risk of breast cancer by four-to-eightfold.

The study of 2,733 British women also found a double mastectomy did not improve survival rates for patients with the mutation 10 years later.

An expert said women should take time to decide if surgery was for them.

BRCA has been dubbed the 'Angelina Jolie gene', after the actress revealed she underwent surgery on learning she had an up to 87% chance of developing breast cancer.

Mutations in these genes stop DNA repairing itself and increase the risk of cancer developing.

They are also linked to ovarian and prostate cancers, as well as breast cancer.

The study, published in The Lancet Oncology, found 12% of 2,733 women aged 18 to 40 treated for breast cancer at 127 hospitals across the UK between 2000 and 2008 had a BRCA mutation.

The women's medical records were tracked for up to 10 years.

'More time to decide'


Continue reading at BBC »